RRC ID |
30168
|
著者 |
Kogoma T, von Meyenburg K.
|
タイトル |
The origin of replication, oriC, and the dnaA protein are dispensable in stable DNA replication (sdrA) mutants of Escherichia coli K-12.
|
ジャーナル |
EMBO J
|
Abstract |
The sdrA224 mutants of Escherichia coli K-12, capable of continued DNA replication in the absence of protein synthesis (stable DNA replication), tolerate inactivation of the dnaA gene by insertion of transposon Tn10. Furthermore, oriC, the origin of E. coli chromosome replication, can be deleted from the chromosome of sdrA mutants without loss of viability. The results suggest the presence of a second, normally repressed, initiation system for chromosome replication alternative to the 'normal' dnaA+ oriC+-dependent initiation mechanism.
|
巻・号 |
2(3)
|
ページ |
463-8
|
公開日 |
1983-1-1
|
DOI |
10.1002/j.1460-2075.1983.tb01445.x
|
PMID |
11894964
|
PMC |
PMC555155
|
MeSH |
Bacterial Proteins / genetics*
DNA Replication*
DNA, Bacterial / biosynthesis*
DNA-Binding Proteins / genetics*
Escherichia coli / genetics*
Genes, Viral
Mutagenesis
Replication Origin*
Transposases
|
IF |
9.889
|
引用数 |
103
|
WOS 分野
|
BIOCHEMISTRY & MOLECULAR BIOLOGY
CELL BIOLOGY
|
リソース情報 |
原核生物(大腸菌) |
ME9157
ME9156
ME9158
ME9139
ME9138
ME9131 |