論文 - 詳細
| RRC ID | 30562 |
|---|---|
| 著者 | Kojima Y, Wakita J, Inayoshi Y, Suzuki R, Yamada Y, Kaneoka H, Nishijima K, Iijima S. |
| タイトル | Galactosylation of human erythropoietin produced by chimeric chickens expressing galactosyltransferase. |
| ジャーナル | J Biosci Bioeng |
| Abstract |
Human erythropoietin produced in the egg white of chimeric chicken contains N-glycan with lower amounts of terminal galactose and sialic acid; therefore, the chicken galactosyltransferase gene was introduced together with the human erythropoietin gene by a retroviral vector. We found that erythropoietin accumulated in the egg white was partially galactosylated. |
| 巻・号 | 117(6) |
| ページ | 676-9 |
| 公開日 | 2014-6-1 |
| DOI | 10.1016/j.jbiosc.2013.11.010 |
| PII | S1389-1723(13)00432-5 |
| PMID | 24355574 |
| MeSH | Animals Animals, Genetically Modified / genetics Avian Proteins / biosynthesis Avian Proteins / genetics Chick Embryo Chickens / genetics* Egg Proteins / metabolism Erythropoietin / genetics Erythropoietin / metabolism* Galactose / metabolism* Galactosyltransferases / biosynthesis Galactosyltransferases / genetics Glycosylation Humans Plasmids Protein Processing, Post-Translational* Vesiculovirus / genetics |
| IF | 2.366 |
| 引用数 | 5 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ニワトリ・ウズラ | |