| RRC ID |
31721
|
| Author |
Yazawa K, Mikami Y, Sakamoto T, Ueno Y, Morisaki N, Iwasaki S, Furihata K.
|
| Title |
Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species.
|
| Journal |
Antimicrob Agents Chemother
|
| Abstract |
A survey of five Nocardia spp. with respect to susceptibility towards three macrolides (erythromycin, rokitamycin, and midecamycin) showed that the Nocardia spp. have different susceptibility profiles. Most of the resistance was due to the inactivation of the macrolides by phosphorylation, glycosylation, reduction, deacylation, or a combination thereof.
|
| Volume |
38(9)
|
| Pages |
2197-9
|
| Published |
1994-9-1
|
| DOI |
10.1128/AAC.38.9.2197
|
| PMID |
7811046
|
| PMC |
PMC284711
|
| MeSH |
Biotransformation
Erythromycin / pharmacokinetics*
Erythromycin / pharmacology
Glycosylation
Inactivation, Metabolic
Leucomycins / pharmacokinetics*
Leucomycins / pharmacology
Microbial Sensitivity Tests
Miocamycin / analogs & derivatives*
Miocamycin / pharmacokinetics
Miocamycin / pharmacology
Nocardia / drug effects*
Nocardia / metabolism*
Oxidation-Reduction
Phosphorylation
|
| IF |
4.904
|
| Times Cited |
8
|
|
WOS Category
|
PHARMACOLOGY & PHARMACY
MICROBIOLOGY
|
| Resource |
| Pathogenic microorganisms |
IFM 0236
IFM 0239
IFM 0284
IFM 0310
IFM 0339 |
