RRC ID |
31721
|
著者 |
Yazawa K, Mikami Y, Sakamoto T, Ueno Y, Morisaki N, Iwasaki S, Furihata K.
|
タイトル |
Inactivation of the macrolide antibiotics erythromycin, midecamycin, and rokitamycin by pathogenic Nocardia species.
|
ジャーナル |
Antimicrob Agents Chemother
|
Abstract |
A survey of five Nocardia spp. with respect to susceptibility towards three macrolides (erythromycin, rokitamycin, and midecamycin) showed that the Nocardia spp. have different susceptibility profiles. Most of the resistance was due to the inactivation of the macrolides by phosphorylation, glycosylation, reduction, deacylation, or a combination thereof.
|
巻・号 |
38(9)
|
ページ |
2197-9
|
公開日 |
1994-9-1
|
DOI |
10.1128/AAC.38.9.2197
|
PMID |
7811046
|
PMC |
PMC284711
|
MeSH |
Biotransformation
Erythromycin / pharmacokinetics*
Erythromycin / pharmacology
Glycosylation
Inactivation, Metabolic
Leucomycins / pharmacokinetics*
Leucomycins / pharmacology
Microbial Sensitivity Tests
Miocamycin / analogs & derivatives*
Miocamycin / pharmacokinetics
Miocamycin / pharmacology
Nocardia / drug effects*
Nocardia / metabolism*
Oxidation-Reduction
Phosphorylation
|
IF |
4.904
|
引用数 |
8
|
WOS 分野
|
PHARMACOLOGY & PHARMACY
MICROBIOLOGY
|
リソース情報 |
病原微生物 |
IFM 0236
IFM 0239
IFM 0284
IFM 0310
IFM 0339 |