論文 - 詳細
| RRC ID | 31864 |
|---|---|
| 著者 | Arai T, Uno J, Horimi I, Fukushima K. |
| タイトル | Isolation of neocopiamycin A from Streptomyces hygroscopicus var. crystallogenes, the copiamycin source. |
| ジャーナル | J Antibiot (Tokyo) |
| Abstract |
Fermentation of Streptomyces hygroscopicus var. crystallogenes, the copiamycin source, yielded several minor components with antifungal activity. One of these minor components, neocopiamycin A, was isolated and characterized. The structure of neocopiamycin A was determined as N-demethylcopiamycin on the basis of spectroscopic evidence. The antibiotic was found to be more active against Gram-positive bacteria and fungi but less toxic than copiamycin. |
| 巻・号 | 37(2) |
| ページ | 103-9 |
| 公開日 | 1984-2-1 |
| DOI | 10.7164/antibiotics.37.103 |
| PMID | 6546749 |
| MeSH | Animals Anti-Bacterial Agents / isolation & purification* Anti-Bacterial Agents / pharmacology Anti-Bacterial Agents / toxicity Chemical Phenomena Chemistry Fermentation Lactones / isolation & purification Lactones / pharmacology Magnetic Resonance Spectroscopy Mass Spectrometry Mice Mice, Inbred Strains Microbial Sensitivity Tests Streptomyces / metabolism* |
| IF | 2.668 |
| 引用数 | 25 |
| WOS 分野 | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY IMMUNOLOGY |
| リソース情報 | |
| 病原微生物 | IFM 0042 IFM 0082 IFM 40001 IFM 40002 IFM 40003 IFM 40004 IFM 40005 IFM 40007 IFM 40008 IFM 40009 IFM 40017 IFM 40018 IFM 40019 IFM 40020 IFM 40021 IFM 40025 IFM 40037 IFM 40038 IFM 40047 IFM 40065 IFM 40066 IFM 40068 IFM 40099 IFM 40607 IFM 40727 IFM 40732 IFM 40737 IFM 40750 IFM 40751 IFM 40752 |