RRC ID 31927
著者 Nakadate S, Nozawa K, Sato H, Horie H, Fujii Y, Nagai M, Hosoe T, Kawai K, Yaguchi T.
タイトル Antifungal cyclic depsipeptide, eujavanicin A, isolated from Eupenicillium javanicum.
ジャーナル J Nat Prod
Abstract In the course of searching for new antifungal agents, a new cyclic depsipeptide, eujavanicin A (1), was isolated from Eupenicillium javanicum as an antifungal agent against the human pathogenic filamentous fungus Aspergillus fumigatus. The structure of 1 was established by spectroscopic and chemical investigations. The absolute stereochemistry was elucidated by Marfey's method and by chiral HPLC analysis.
巻・号 71(9)
ページ 1640-2
公開日 2008-9-1
DOI 10.1021/np8002904
PMID 18771240
MeSH Antifungal Agents / chemistry Antifungal Agents / isolation & purification* Antifungal Agents / pharmacology* Aspergillus fumigatus / drug effects* Bacillus subtilis / drug effects Depsipeptides / chemistry Depsipeptides / isolation & purification* Depsipeptides / pharmacology* Escherichia coli / drug effects Humans Japan Microbial Sensitivity Tests Molecular Structure Salmonella enteritidis / drug effects Staphylococcus aureus / drug effects
IF 3.782
引用数 12
WOS 分野 PLANT SCIENCES PHARMACOLOGY & PHARMACY CHEMISTRY, MEDICINAL
リソース情報
病原微生物 IFM 54704