| RRC ID |
31937
|
| 著者 |
Nemoto A, Tanaka Y, Karasaki Y, Komaki H, Yazawa K, Mikami Y, Tojo T, Kadowaki K, Tsuda M, Kobayashi J.
|
| タイトル |
Brasiliquinones A, B and C, new benz[alpha]anthraquinone antibiotics from Nocardia brasiliensis. I. Producing strain, isolation and biological activities of the antibiotics.
|
| ジャーナル |
J Antibiot (Tokyo)
|
| Abstract |
New benz[alpha]anthraquinone antibiotics (brasiliquinones A, B and C) with an ethyl group at C-3 were isolated. The producer was identified as Nocardia brasiliensis. The antibiotics were active against Gram-positive bacteria including Mycobacterium sp., but not active against Gram-negative bacteria or fungi. They were also active against multiple drug-resistant P388/ADR tumor cells.
|
| 巻・号 |
50(1)
|
| ページ |
18-21
|
| 公開日 |
1997-1-1
|
| DOI |
10.7164/antibiotics.50.18
|
| PMID |
9066761
|
| MeSH |
Animals
Anthraquinones / isolation & purification
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification*
Anti-Bacterial Agents / pharmacology
Fermentation
Mice
Nocardia / classification
Nocardia / metabolism*
Tumor Cells, Cultured
|
| IF |
2.668
|
| 引用数 |
22
|
|
WOS 分野
|
PHARMACOLOGY & PHARMACY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
IMMUNOLOGY
MICROBIOLOGY
|
| リソース情報 |
| 病原微生物 |
IFM 0089
IFM 40213 |
