RRC ID 31937
Author Nemoto A, Tanaka Y, Karasaki Y, Komaki H, Yazawa K, Mikami Y, Tojo T, Kadowaki K, Tsuda M, Kobayashi J.
Title Brasiliquinones A, B and C, new benz[alpha]anthraquinone antibiotics from Nocardia brasiliensis. I. Producing strain, isolation and biological activities of the antibiotics.
Journal J. Antibiot.
Abstract New benz[alpha]anthraquinone antibiotics (brasiliquinones A, B and C) with an ethyl group at C-3 were isolated. The producer was identified as Nocardia brasiliensis. The antibiotics were active against Gram-positive bacteria including Mycobacterium sp., but not active against Gram-negative bacteria or fungi. They were also active against multiple drug-resistant P388/ADR tumor cells.
Volume 50(1)
Pages 18-21
Published 1997-1
PMID 9066761
MeSH Animals Anthraquinones / isolation & purification Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification* Anti-Bacterial Agents / pharmacology Fermentation Mice Nocardia / classification Nocardia / metabolism* Tumor Cells, Cultured
IF 2.033
Times Cited 20
WOS Category PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY
Resource
Pathogenic microorganisms IFM 0089 IFM 40213