Reference - Detail
| RRC ID | 32198 |
|---|---|
| Author | Tachibana T, Matsuyama T, Ito M, Mitsuyama M. |
| Title | Sporothrix schenckii thermo-intolerant mutants losing fatal visceral infectivity but retaining high cutaneous infectivity. |
| Journal | Med Mycol |
| Abstract |
Four mutants of the Sporothrix schenckii lung isolate IFM 41598 were isolated by their inability to form colonies on a Sabouraud glucose agar plate incubated at 37 degrees C for 4 days. In contrast to the parent IFM 41598, these thermo-intolerant mutants were all defective in producing fatal visceral infections in mice, even though they retained infectivity in footpad tissues with a small fungal inoculum (approximately equals 10 cfu). |
| Volume | 39(3) |
| Pages | 295-8 |
| Published | 2001-6-1 |
| DOI | 10.1080/mmy.39.3.295.298 |
| PMID | 11446534 |
| MeSH | Animals Dermatomycoses / microbiology* Dermatomycoses / physiopathology Foot / microbiology Genes, Fungal Humans Lung Diseases, Fungal / microbiology Male Mice Mice, Inbred BALB C Mutation* Nitrosoguanidines Sporothrix / genetics* Sporothrix / pathogenicity* Sporotrichosis / microbiology* Sporotrichosis / physiopathology Temperature Virulence |
| IF | 2.822 |
| Times Cited | 6 |
| WOS Category | VETERINARY SCIENCES MYCOLOGY INFECTIOUS DISEASES |
| Resource | |
| Pathogenic microorganisms | IFM 5906 IFM 41598 IFM 46010 IFM 46011 IFM 46365 |