RRC ID 32206
Author Kobayashi H, Sano A, Aragane N, Fukuoka M, Tanaka M, Kawaura F, Fukuno Y, Matsuishi E, Hayashi S.
Title Disseminated infection by Bipolaris spicifera in an immunocompetent subject.
Journal Med Mycol
Abstract We report a case of disseminated infection due to Bipolaris spicifera in an immunocompetent male. Histopathological studies of lymph node, lung, and liver biopsy specimens showed a dark pigmented, granular fungal structure inside the granuloma. The disease was accompanied by the unusual feature of positive lupus anticoagulant in serum and low-density areas expanding along the portal vein in the liver. The disease responded to combination therapy with intravenous amphotericin B and voriconazole, but recurred during oral itraconazole. The fungal isolate from the lymph node was identified as Bipolaris spicifera on the basis of morphology and molecular biological data.
Volume 46(4)
Pages 361-5
Published 2008-6-1
DOI 10.1080/13693780701883490
PII 791510451
PMID 18415844
MeSH Adult Amphotericin B / therapeutic use Ascomycota / cytology Ascomycota / isolation & purification* DNA, Fungal / analysis DNA, Ribosomal / analysis Humans Immunocompetence Itraconazole / therapeutic use Lymph Nodes / microbiology Male Mycoses / drug therapy Mycoses / immunology Mycoses / pathology* Pyrimidines / therapeutic use Sequence Analysis, DNA Triazoles / therapeutic use Voriconazole
IF 2.822
Times Cited 17
Pathogenic microorganisms IFM 41459 IFM 41460 IFM 41474 IFM 52187 IFM 52973 IFM 55164