論文 - 詳細
| RRC ID | 32533 |
|---|---|
| 著者 | Hiroi M, Ohkura M, Nakai J, Masuda N, Hashimoto K, Inoue K, Fiala A, Tabata T. |
| タイトル | Principal component analysis of odor coding at the level of third-order olfactory neurons in Drosophila. |
| ジャーナル | Genes Cells |
| Abstract |
Olfactory information in Drosophila is conveyed by projection neurons from olfactory sensory neurons to Kenyon cells (KCs) in the mushroom body (MB). A subset of KCs responds to a given odor molecule, and the combination of these KCs represents a part of the neuronal olfactory code. KCs are also thought to function as coincidence detectors for memory formation, associating odor information with a coincident punishment or reward stimulus. Associative conditioning has been shown to modify KC output. This plasticity occurs in the vertical lobes of MBs containing α/α' branches of KCs, which is shown by measuring the average Ca(2+) levels in the branch of each lobe. We devised a method to quantitatively describe the population activity patterns recorded from axons of >1000 KCs at the α/α' branches using two-photon Ca(2+) imaging. Principal component analysis of the population activity patterns clearly differentiated the responses to distinct odors. |
| 巻・号 | 18(12) |
| ページ | 1070-81 |
| 公開日 | 2013-12-1 |
| DOI | 10.1111/gtc.12094 |
| PMID | 24118654 |
| MeSH | Animals Axons / physiology Cyclohexanols / pharmacology Drosophila / physiology* Mushroom Bodies / cytology Mushroom Bodies / physiology Octanols / pharmacology Odorants* Olfactory Receptor Neurons / physiology* Principal Component Analysis Smell |
| IF | 1.655 |
| 引用数 | 4 |
| WOS 分野 | GENETICS & HEREDITY CELL BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 各媒体での言及数の合計 | 0 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ショウジョウバエ | OK107 gal4 driver |