論文 - 詳細
RRC ID | 32626 |
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著者 | Hosoe T, Nozawa K, Kawahara N, Fukushima K, Nishimura K, Miyaji M, Kawai K. |
タイトル | Isolation of a new potent cytotoxic pigment along with indigotin from the pathogenic basidiomycetous fungus Schizophyllum commune. |
ジャーナル | Mycopathologia |
Abstract |
An indole derivative, schizocommunin, was isolated along with indigotin (indigo), indirubin, isatin, and tryptanthrin, from the liquid culture medium in which a culture of Schizophyllum commune, isolated from the bronchus of a human patient with allergic bronchopulmonary mycosis, had been grown. The structure of schizocommunin was established by spectroscopic investigation. Schizocommunin showed the strong cytotoxicity against murine lymphoma cells. The assignments of the 1H- and 13C-NMR signals of indigotin were also listed. |
巻・号 | 146(1) |
ページ | 9-12 |
公開日 | 1999-1-1 |
DOI | 10.1023/a:1007082619328 |
PMID | 10721515 |
MeSH | Animals Antineoplastic Agents / isolation & purification* Indigo Carmine Indoles / isolation & purification* Indoles / toxicity Lymphoma Mice Nuclear Magnetic Resonance, Biomolecular Pigments, Biological / isolation & purification Schizophyllum / chemistry* Tumor Cells, Cultured |
IF | 2.452 |
引用数 | 31 |
WOS 分野 | MYCOLOGY |
リソース情報 | |
病原微生物 | IFM 46788 |