| RRC ID |
3307
|
| Author |
Eydallin G, Viale AM, Morán-Zorzano MT, Muñoz FJ, Montero M, Baroja-Fernández E, Pozueta-Romero J.
|
| Title |
Genome-wide screening of genes affecting glycogen metabolism in Escherichia coli K-12.
|
| Journal |
FEBS Lett
|
| Abstract |
A systematic and comprehensive gene-disrupted mutant collection of E. coli K-12 was used to identify genes whose deletions affect glycogen accumulation. Of the 3985 non-essential gene mutants of the collection, 35 displayed a glycogen-excess phenotype, whereas 30 displayed either glycogen-less or glycogen-deficient phenotypes. The genes whose deletions affect glycogen accumulation were classified into various functional categories, including energy production, envelope composition and integrity, protein translation and stability, transport of inorganic ions and nucleotides, and metabolism of carbohydrates and amino acids. The overall data indicate that glycogen metabolism is highly interconnected with a wide variety of cellular processes in E. coli.
|
| Volume |
581(16)
|
| Pages |
2947-53
|
| Published |
2007-6-26
|
| DOI |
10.1016/j.febslet.2007.05.044
|
| PII |
S0014-5793(07)00571-6
|
| PMID |
17543954
|
| MeSH |
Amino Acids / metabolism
Bacterial Outer Membrane Proteins / metabolism
Carbohydrate Metabolism / genetics
Energy Metabolism / genetics
Escherichia coli K12 / genetics*
Escherichia coli K12 / metabolism*
Gene Deletion
Genes, Bacterial
Genome, Bacterial*
Genomics / methods
Glycogen / metabolism*
|
| IF |
3.057
|
| Times Cited |
41
|
|
WOS Category
|
BIOPHYSICS
BIOCHEMISTRY & MOLECULAR BIOLOGY
CELL BIOLOGY
|
| Resource |
| Prokaryotes E. coli |
ME9062 (BW25113)
Keio collection |
