論文 - 詳細
| RRC ID | 3328 |
|---|---|
| 著者 | Ogawa T, Murakami K, Mori H, Ishii N, Tomita M, Yoshin M. |
| タイトル | Role of phosphoenolpyruvate in the NADP-isocitrate dehydrogenase and isocitrate lyase reaction in Escherichia coli. |
| ジャーナル | J Bacteriol |
| Abstract |
Phosphoenolpyruvate inhibited Escherichia coli NADP-isocitrate dehydrogenase allosterically (Ki of 0.31 mM) and isocitrate lyase uncompetitively (Ki' of 0.893 mM). Phosphoenolpyruvate enhances the uncompetitive inhibition of isocitrate lyase by increasing isocitrate, which protects isocitrate dehydrogenase from the inhibition, and contributes to the control through the tricarboxylic acid cycle and glyoxylate shunt. |
| 巻・号 | 189(3) |
| ページ | 1176-8 |
| 公開日 | 2007-2-1 |
| DOI | 10.1128/JB.01628-06 |
| PII | JB.01628-06 |
| PMID | 17142397 |
| PMC | PMC1797289 |
| MeSH | Escherichia coli / drug effects Escherichia coli / enzymology Escherichia coli / metabolism* Isocitrate Dehydrogenase / antagonists & inhibitors Isocitrate Dehydrogenase / metabolism* Isocitrate Lyase / antagonists & inhibitors Isocitrate Lyase / metabolism* Isocitrates / metabolism Isocitrates / pharmacology Kinetics NADP / metabolism Phosphoenolpyruvate / metabolism* Phosphoenolpyruvate / pharmacology |
| IF | 3.006 |
| 引用数 | 13 |
| WOS 分野 | MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 7 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 原核生物(大腸菌) | ? W3110 |