論文 - 詳細
RRC ID | 3343 |
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著者 | Weiss B. |
タイトル | YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12. |
ジャーナル | J Bacteriol |
Abstract |
Exogenous thymine must be converted to thymidine to enable a thyA (thymidylate synthase) mutant to grow. The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium. |
巻・号 | 189(5) |
ページ | 2186-9 |
公開日 | 2007-3-1 |
DOI | 10.1128/JB.01645-06 |
PII | JB.01645-06 |
PMID | 17189366 |
PMC | PMC1855703 |
MeSH | Deoxyuracil Nucleotides / metabolism* Escherichia coli / metabolism* Escherichia coli Proteins / physiology* N-Glycosyl Hydrolases / physiology* Phosphorylation Thymidylate Synthase / physiology Thymine / metabolism* |
IF | 3.006 |
引用数 | 12 |
WOS 分野 | MICROBIOLOGY |
リソース情報 | |
原核生物(大腸菌) |