Reference - Detail
|Author||Molle V, Nakaura Y, Shivers RP, Yamaguchi H, Losick R, Fujita Y, Sonenshein AL.|
|Title||Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.|
Additional targets of CodY, a GTP-activated repressor of early stationary-phase genes in Bacillus subtilis, were identified by combining chromatin immunoprecipitation, DNA microarray hybridization, and gel mobility shift assays. The direct targets of CodY newly identified by this approach included regulatory genes for sporulation, genes that are likely to encode transporters for amino acids and sugars, and the genes for biosynthesis of branched-chain amino acids.
|MeSH||Bacillus subtilis / genetics Bacillus subtilis / growth & development Bacillus subtilis / metabolism* Bacterial Proteins / genetics Bacterial Proteins / metabolism* Chromatin DNA, Bacterial / metabolism DNA-Binding Proteins* Gene Expression Regulation, Bacterial* Lac Operon / genetics Mutation Oligonucleotide Array Sequence Analysis / methods* Precipitin Tests / methods* Promoter Regions, Genetic Recombinant Fusion Proteins Repressor Proteins / genetics Repressor Proteins / metabolism* Transcription, Genetic|
|Prokaryotes B. subtilis||MBS239 MBS218 MBS219 MBS230 MBS231 MBS232 MBS233 MBS234 MBS235 MBS236 MBS237 MBS238 MBS240 MBS242|