RRC ID 3387
著者 Ji YJ, Singaravelu G, Ahnn J.
タイトル RNT-1 regulation in C. elegans.
ジャーナル J Cell Biochem
Abstract RUNXs are important transcription factors, which are involved in animal development and human carcinogenesis. RNT-1, the only homologue of RUNXs, in Caenorhabditis elegans (C. elegans) has been identified and viable mutant animals of rnt-1 gene have been isolated and characterized recently. Genetic analyses using rnt-1 mutants have shown that RNT-1 is regulated by TGFbeta- and Wnt-signaling pathways in the body size regulation and male tail development. Here, we review our current understanding of RNT-1 functions in these signaling pathways. Furthermore, future prospects of RNT-1 and BRO-1 studies in C. elegans are discussed in this review.
巻・号 96(1)
ページ 8-15
公開日 2005-9-1
DOI 10.1002/jcb.20423
PMID 15988754
MeSH Animals Caenorhabditis elegans / genetics* Caenorhabditis elegans / physiology Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / physiology* Gene Expression Regulation / physiology* Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Signal Transduction / physiology Transcription Factors / genetics Transcription Factors / physiology* Transforming Growth Factor beta / physiology
IF 4.237
引用数 3
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY CELL BIOLOGY
リソース情報
線虫 tm388 tm658