RRC ID 35192
Author Vardar-Schara G, Maeda T, Wood TK.
Title Metabolically engineered bacteria for producing hydrogen via fermentation.
Journal Microb Biotechnol
Abstract Hydrogen, the most abundant and lightest element in the universe, has much potential as a future energy source. Hydrogenases catalyse one of the simplest chemical reactions, 2H(+) + 2e(-) ↔ H(2), yet their structure is very complex. Biologically, hydrogen can be produced via photosynthetic or fermentative routes. This review provides an overview of microbial production of hydrogen by fermentation (currently the more favourable route) and focuses on biochemical pathways, theoretical hydrogen yields and hydrogenase structure. In addition, several examples of metabolic engineering to enhance fermentative hydrogen production are presented along with some examples of expression of heterologous hydrogenases for enhanced hydrogen production.
Volume 1(2)
Pages 107-25
Published 2008-3
DOI 10.1111/j.1751-7915.2007.00009.x
PMID 21261829
PMC PMC3864445
MeSH Bacteria / chemistry Bacteria / enzymology Bacteria / genetics* Bacteria / metabolism* Bacterial Proteins / chemistry Bacterial Proteins / genetics Bacterial Proteins / metabolism Fermentation Genetic Engineering* Hydrogen / metabolism* Hydrogenase / chemistry Hydrogenase / genetics Hydrogenase / metabolism Photosynthesis
IF 3.913
Times Cited 52
Prokaryotes E. coli Review