| RRC ID |
35924
|
| 著者 |
Shao J, He Y, Li F, Zhang H, Chen A, Luo S, Gu JD.
|
| タイトル |
Growth inhibition and possible mechanism of oleamide against the toxin-producing cyanobacterium Microcystis aeruginosa NIES-843.
|
| ジャーナル |
Ecotoxicology
|
| Abstract |
Oleamide, a fatty acid derivative, shows inhibitory effect against the bloom-forming cyanobacterium Microcystis aeruginosa. The EC50 of oleamide on the growth of M. aeruginosa NIES-843 was 8.60 ± 1.20 mg/L. In order to elucidate the possible mechanism of toxicity of oleamide against M. aeruginosa, chlorophyll fluorescence transient, cellular ultrastructure, fatty acids composition and the transcription of the mcyB gene involved in microcystins synthesis were studied. The results of chlorophyll fluorescence transient showed that oleamide could destruct the electron accepting side of the photosystem II of M. aeruginosa NIES-843. Cellular ultrastructure examination indicated that the destruction of fatty acid constituents, the distortion of thylakoid membrane and the loss of integrity of cell membrane were associated with oleamide treatment and concentration. The damage of cellular membrane increased the release of microcystins from intact cells into the medium. Results presented in this study provide new information on the possible mechanisms involved and potential utilization of oleamide as an algicide in cyanobacterial bloom control.
|
| 巻・号 |
25(1)
|
| ページ |
225-33
|
| 公開日 |
2016-1-1
|
| DOI |
10.1007/s10646-015-1582-x
|
| PII |
10.1007/s10646-015-1582-x
|
| PMID |
26547872
|
| MeSH |
Cell Membrane / drug effects
Microcystins / metabolism*
Microcystis / drug effects*
Microcystis / genetics
Microcystis / metabolism
Microcystis / ultrastructure
Oleic Acids / pharmacology*
Pest Control
Photosystem II Protein Complex / metabolism
Thylakoids / drug effects
|
| IF |
2.535
|
| 引用数 |
5
|
|
WOS 分野
|
ENVIRONMENTAL SCIENCES
ECOLOGY
TOXICOLOGY
|
| リソース情報 |
| 藻類 |
NIES-843 |
