Reference - Detail
| RRC ID | 3634 |
|---|---|
| Author | Sun H, Nelms BL, Sleiman SF, Chamberlin HM, Hanna-Rose W. |
| Title | Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related Zinc-Finger ZIM proteins. |
| Journal | Genetics |
| Abstract |
The previously reported negative regulatory activity of HIM-8 on the Sox protein EGL-13 is shared by the HIM-8-related ZIM proteins. Furthermore, mutation of HIM-8 can modulate the effects of substitution mutations in the DNA-binding domains of at least four other transcription factors, suggesting broad regulatory activity by HIM-8. |
| Volume | 177(2) |
| Pages | 1221-6 |
| Published | 2007-10-1 |
| DOI | 10.1534/genetics.107.070847 |
| PII | genetics.107.070847 |
| PMID | 17720937 |
| PMC | PMC2034626 |
| MeSH | Amino Acid Substitution Animals Caenorhabditis elegans Proteins / genetics* Caenorhabditis elegans Proteins / physiology Cell Cycle Proteins / genetics Cell Cycle Proteins / physiology* Chromosomal Proteins, Non-Histone / physiology* DNA-Binding Proteins / genetics Gene Expression Regulation Genes, Helminth Transcription Factors / physiology* Zinc Fingers |
| IF | 4.015 |
| Times Cited | 7 |
| WOS Category | GENETICS & HEREDITY |
| Resource | |
| C.elegans | tm1813 tm574 tm2303 tm607 tm611 |