RRC ID 3634
Author Sun H, Nelms BL, Sleiman SF, Chamberlin HM, Hanna-Rose W.
Title Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related Zinc-Finger ZIM proteins.
Journal Genetics
Abstract The previously reported negative regulatory activity of HIM-8 on the Sox protein EGL-13 is shared by the HIM-8-related ZIM proteins. Furthermore, mutation of HIM-8 can modulate the effects of substitution mutations in the DNA-binding domains of at least four other transcription factors, suggesting broad regulatory activity by HIM-8.
Volume 177(2)
Pages 1221-6
Published 2007-10-1
DOI 10.1534/genetics.107.070847
PII genetics.107.070847
PMID 17720937
PMC PMC2034626
MeSH Amino Acid Substitution Animals Caenorhabditis elegans Proteins / genetics* Caenorhabditis elegans Proteins / physiology Cell Cycle Proteins / genetics Cell Cycle Proteins / physiology* Chromosomal Proteins, Non-Histone / physiology* DNA-Binding Proteins / genetics Gene Expression Regulation Genes, Helminth Transcription Factors / physiology* Zinc Fingers
IF 4.015
Times Cited 7
WOS Category GENETICS & HEREDITY
Resource
C.elegans tm1813 tm574 tm2303 tm607 tm611