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  • Search Condition : Filter (MeSH = Amino Acid Substitution)
Species Resource
Tropical clawed frog Ivory Coast line Evolution of mammalian Opn5 as a specialized UV-absorbing pigment by a single amino acid mutation.
Rice W0106 , W0120 , W0157 , W0574 , W0593 , W0630 , W1294 , W1666 , W1715 , W1807 , ... Natural variation of the RICE FLOWERING LOCUS T 1 contributes to flowering time divergence in rice.
DNA material Slp4-a (RDB03421) , pEF-T7-mouse Slac2-b (RDB15095) , pEF-FLAG-mouse Munc18-1 (RDB15177). Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
DNA material pf Six1 (RDB05730) Impaired interactions between mouse Eyal harboring mutations found in patients with branchio-oto-renal syndrome and Six, Dach, and G proteins.
Drosophila A single-amino-acid change of the gustatory receptor gene, Gr5a, has a major effect on trehalose sensitivity in a natural population of Drosophila melanogaster.
Arabidopsis / Cultured plant cells, genes pda08201 ACBP4 and ACBP5, novel Arabidopsis acyl-CoA-binding proteins with kelch motifs that bind oleoyl-CoA.
Rice W2002 , W2012 , W1865 , W1819 , W1294 , W1943 , W1944 , W025 , W1468 , W1647 , ... Allelic diversification at the C (OsC1) locus of wild and cultivated rice: nucleotide changes associated with phenotypes.
Yeast FY9906(TP4-1D) Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe.
Yeast BY20282(IFO11023) , BY20107(IFO1992) , BY21386(IFO0211) , BY21389(IFO1128) , BY20544(IFO11024) , BY21387(IFO0316) , BY20597(IFO1267) Occurrence, horizontal transfer and degeneration of VDE intein family in Saccharomycete yeasts.
Pathogenic microorganisms GTC 1966 , GTC 1967 , GTC 2001 , GTC 1234 , GTC 262 , GTC 269 , GTC 542 , GTC 244 , GTC 423? , GTC 431 , ... First Streptococcus agalactiae isolates highly resistant to quinolones, with point mutations in gyrA and parC.
Pathogenic microorganisms RIMD 0509952 , RIMD 05091612? , RIMD 05091546? Urease activity of enterohaemorrhagic Escherichia coli depends on a specific one-base substitution in ureD.
Pathogenic microorganisms N. gonorrhoeae? Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan.
Human and Animal Cells KU812 Affinity improvement of the high-affinity immunoglobulin E receptor by phage display.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , CSII-EF-MCS (RDB04378). Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein.
DNA material pEGFP-SOD1_WT (RDB13390) , pEGFP-SOD1_G85R (RDB13391) , pEGFP-SOD1_G93A (RDB13392). The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS.
DNA material pcDNA3-SOD1-FLAG_WT (RDB13386) , pGEX6p-1-SOD1_WT (RDB13393) , pcDNA3-SOD1-FLAG_G85R (RDB13387) , pcDNA3-SOD1-FLAG_G93A (RDB13388) , pGEX6p-1-SOD1_G93A (RDB13394). Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
Yeast NA Nuclear localization domains of GATA activator Gln3 are required for transcription of target genes through dephosphorylation in Saccharomyces cerevisiae.
DNA material pMXs-KITWT-IRES-GFP (RDB13470) , pMXs-KITN508I-IRES-GFP (RDB13471). A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization.
Prokaryotes E. coli ? Analysis of the impact of a uracil DNA glycosylase attenuated in AP-DNA binding in maintenance of the genomic integrity in Escherichia coli.
Prokaryotes E. coli JW2860-KC? The dimeric SOS mutagenesis protein UmuD is active as a monomer.