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Species Resource
Zebrafish Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation.
Prokaryotes E. coli Anti-MreB antibody Superstructure formation by RodZ hexamers of Shigella sonnei maintains the rod shape of bacilli.
DNA material Rat alpha-Antitryspin RRRRSL mutant (RDB03410) , Rat alpha-Antitrypsin RRRRSQ mutant (RDB03411) Engineering of alpha1-antitrypsin variants selective for subtilisin-like proprotein convertases PACE4 and PC6: importance of the P2' residue in stable complex formation of the serpin with proprotein convertase.
Human and Animal Cells Hep G2(RCB1648) A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus.
Algae NIES-2880 , NIES-2887 Accelerated evolution associated with genome reduction in a free-living prokaryote.
Drosophila A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands.
Silkworms Effects of amino acid substitutions on the biological activity of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).
Chicken / Quail Amino acid substitution in the Cυ3 domain causes either elevation or reduction of IgY uptake into egg yolks of quail.
Human and Animal Cells 293(RCB1637) Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.
Prokaryotes E. coli JM109 Identification and characterization of a translation arrest motif in VemP by systematic mutational analysis.
General Microbes JCM 18338 , JCM 20691 Investigation of the thermophilic mechanism in the genus Porphyrobacter by comparative genomic analysis.
DNA material Thermophile Gene Expression Plasmid (RDB15969) Increasing the Thermostable Sugar-1-Phosphate Nucleotidylyltransferase Activities of the Archaeal ST0452 Protein through Site Saturation Mutagenesis of the 97th Amino Acid Position.
DNA material pEF6-FLAG-human IRAK1 (RDB16723) , pCDNA3-FLAG-human TRAF6 (RDB16722) , pEF6-Myc-mouse Optineurin (RDB16718) , pEF6-Myc-mouse Optineurin(E50K) (RDB16719) , pEF6-Myc-mouse Optineurin(D474N) (RDB16720) , pEF6-Myc-mouse Optineurin(H486R) (RDB16721) Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.
Human and Animal Cells ST2(RCB0224) , RAW 264(RCB0535) Coupling of bone resorption and formation by RANKL reverse signalling.
Prokaryotes E. coli Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin.
Prokaryotes E. coli Point mutations in Escherichia coli DNA pol V that confer resistance to non-cognate DNA damage also alter protein-protein interactions.
Prokaryotes E. coli Impact of Mutating the Key Residues of a Bifunctional 5,10-Methylenetetrahydrofolate Dehydrogenase-Cyclohydrolase from Escherichia coli on Its Activities.
C.elegans Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens.
Cord blood stem cells for research Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia.
Human and Animal Cells CACO-2(RCB0988) Phosphorylation of Ser-525 in βPix impairs Nox1-activating ability in Caco-2 cells.