論文 - 詳細
| RRC ID | 36448 |
|---|---|
| 著者 | Yoshida M, Isa T. |
| タイトル | Signal detection analysis of blindsight in monkeys. |
| ジャーナル | Sci Rep |
| Abstract |
Macaque monkeys with a unilateral lesion in V1 have been used as an animal model of blindsight. While objective proof of blindsight requires that the two aspects of blindsight (residual forced-choice localization and attenuated yes-no detection) should be tested under identical stimulus conditions using bias-free measures of sensitivity, these have not been attained in studies of nonhuman primates. Here we tested two macaque monkeys with a unilateral V1 lesion with two saccade tasks using identical stimuli: a forced-choice (FC) task and a yes-no (YN) task. An analysis based on signal detection theory revealed that sensitivity in the FC task was significantly higher than that in the YN task. Such dissociation of sensitivity between the two tasks was not observed when near-threshold visual stimuli were presented in the normal, unaffected hemifield. These results suggest that the V1-lesioned monkeys resemble the well-studied blindsight patient G.Y., whose visual experience per se was completely abolished. |
| 巻・号 | 5 |
| ページ | 10755 |
| 公開日 | 2015-5-29 |
| DOI | 10.1038/srep10755 |
| PII | srep10755 |
| PMID | 26021856 |
| PMC | PMC4448228 |
| MeSH | Animals Blindness / physiopathology* Humans Macaca Male Photic Stimulation Visual Cortex / physiology* Visual Fields Visual Perception / physiology* |
| IF | 3.998 |
| 引用数 | 9 |
| WOS 分野 | NEUROSCIENCES |
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 12 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
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