RRC ID 36835
Author Tanaka Y, Nagashima H, Bando K, Lu L, Ozaki A, Morita Y, Fukumoto S, Ishii N, Sugawara S.
Title Oral CD103-CD11b+ classical dendritic cells present sublingual antigen and induce Foxp3+ regulatory T cells in draining lymph nodes.
Journal Mucosal Immunol
Abstract Treg cells, and, thus, provide a rationale for developing cDC-based therapeutic approaches in SLIT.
Volume 10(1)
Pages 79-90
Published 2017-1
DOI 10.1038/mi.2016.46
PII mi201646
PMID 27166558
MeSH Animals Antigen Presentation Antigens / immunology Antigens, CD / metabolism CD11b Antigen / metabolism Cell Differentiation Cells, Cultured Dendritic Cells / immunology* Dendritic Cells / transplantation Disease Models, Animal Forkhead Transcription Factors / metabolism Humans Hypersensitivity / immunology Hypersensitivity / therapy* Integrin alpha Chains / metabolism Lymph Nodes / immunology* Lymphocyte Activation Mice Mice, Inbred C57BL Mice, Transgenic Ovalbumin / immunology Sublingual Immunotherapy / methods* T-Lymphocytes, Regulatory / immunology*
IF 7.36
Times Cited 2
WOS Category IMMUNOLOGY
Resource
Mice C57BL/6-Ly5.1(RBRC00144)