論文 - 詳細
| RRC ID | 37859 |
|---|---|
| 著者 | Yamaoka Y, Ohguchi K, Itoh T, Nozawa Y, Akao Y. |
| タイトル | Effects of theaflavins on melanin biosynthesis in mouse b16 melanoma cells. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
In this study, we examined the effects of theaflavins, polyphenols in black tea, on alpha melanocyte-stimulating hormone (alphaMSH)-induced melanogenesis in mouse B16 melanoma cells. Among theaflavins, theaflavin-3,3'-digallate (TF-3) exhibited a potent inhibitory effect on melanogenesis. Our results indicate that the inhibitory effect of TF-3 on melanogenesis is due to suppression of tyrosinase protein and mRNA levels. |
| 巻・号 | 73(6) |
| ページ | 1429-31 |
| 公開日 | 2009-6-1 |
| DOI | 10.1271/bbb.80880 |
| PII | JST.JSTAGE/bbb/80880 |
| PMID | 19502752 |
| MeSH | Animals Base Sequence Biflavonoids / pharmacology* Catechin / pharmacology* Cell Line, Tumor DNA Primers Electrophoresis, Polyacrylamide Gel Melanins / biosynthesis* Melanoma, Experimental / enzymology Melanoma, Experimental / metabolism* Melanoma, Experimental / pathology Mice Monophenol Monooxygenase / genetics Monophenol Monooxygenase / metabolism RNA, Messenger / genetics Reverse Transcriptase Polymerase Chain Reaction |
| IF | 1.516 |
| 引用数 | 7 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | B16 melanoma 4A5(RCB0557) |