RRC ID 38336
著者 Sone Y, Kudo Y, Oba R, Otsuka Y.
タイトル Effects of oxygen concentration on the expression of an antioxidant gene in HepG2.
ジャーナル Biosci Biotechnol Biochem
Abstract To clarify the effects of O(2) concentration (cO(2)) on antioxidant gene expression in human hepatocytes, mRNA expression of HepG2 cells cultured at 1, 3, and 5% cO(2) and atmospheric gas-phase, was measured. The expression of some genes fluctuated depending on the cO(2) in the incubator. This indicates that cO(2) is a critically important factor in the investigation of human biological mechanisms.
巻・号 74(6)
ページ 1267-70
公開日 2010-1-1
DOI 10.1271/bbb.90837
PII JST.JSTAGE/bbb/90837
PMID 20530896
MeSH Antioxidants / metabolism* Dose-Response Relationship, Drug Gene Expression Regulation / drug effects* Hep G2 Cells Humans Oxygen / pharmacology* RNA, Messenger / genetics RNA, Messenger / metabolism
IF 1.516
引用数 1
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY
リソース情報
ヒト・動物細胞