論文 - 詳細
| RRC ID | 38337 |
|---|---|
| 著者 | Fujimori H, Hisama M, Shibayama H, Kawase A, Iwaki M. |
| タイトル | Inhibitory effects of phytoncide solution on melanin biosynthesis. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
To determine the component-activity relationships of phytoncide solutions on inhibitory activity in melanin biosynthesis, four types of phytoncide solution (A-type, AB-type, D-type, and G-type) were evaluated for inhibition of mushroom tyrosinase activity and melanin synthesis on murine B-16 melanoma cells and a human reconstituted skin model. The A-type, AB-type, D-type, and G-type of phytoncide solution treatment resulted in significant inhibition of tyrosinase activity. The amount of melanin was increased by treatment with phytoncide solutions in a concentration-dependent manner on murine B-16 melanoma cells without affecting cell growth. Furthermore, phytoncide solutions also suppressed melanin synthesis in a concentration-dependent manner on a human reconstituted skin model. These effects of A-type solution were superior to those of other solutions. |
| 巻・号 | 74(5) |
| ページ | 918-22 |
| 公開日 | 2010-1-1 |
| DOI | 10.1271/bbb.90700 |
| PII | JST.JSTAGE/bbb/90700 |
| PMID | 20460709 |
| MeSH | Agaricales / enzymology Animals Antioxidants / chemistry Antioxidants / pharmacology Cell Line, Tumor Humans Melanins / biosynthesis* Mice Monophenol Monooxygenase / antagonists & inhibitors Plant Extracts / chemistry* Plant Extracts / pharmacology* Skin / drug effects Skin / metabolism Solutions Volatilization |
| IF | 1.516 |
| 引用数 | 6 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | |