Reference - Detail
RRC ID | 38653 |
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Author | Ito M, Maruhashi M, Sakai N, Mizoue K, Hanada K. |
Title | NG-011 and NG-012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties. |
Journal | J Antibiot (Tokyo) |
Abstract |
NG-011 and NG-012, novel potentiators of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542, together with 3,4-dihydro-6,8-dihydroxy-3-methylisocoumarin. They potentiated the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12). |
Volume | 45(10) |
Pages | 1559-65 |
Published | 1992-10-1 |
DOI | 10.7164/antibiotics.45.1559 |
PMID | 1473982 |
MeSH | Animals Anti-Bacterial Agents / pharmacology* Cells, Cultured Coumarins / chemistry Coumarins / isolation & purification Coumarins / pharmacology Isocoumarins Lactones / chemistry Lactones / isolation & purification Lactones / pharmacology* Nerve Growth Factors / pharmacology* Neurites / drug effects* PC12 Cells Penicillium* / chemistry Penicillium* / classification Penicillium* / isolation & purification Phenols / chemistry Phenols / isolation & purification Phenols / pharmacology* Rats |
IF | 2.668 |
Times Cited | 23 |
WOS Category | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY |
Resource | |
Human and Animal Cells | PC-12(RCB0009) |