RRC ID 39385
著者 Kawaii S, Tomono Y, Katase E, Ogawa K, Yano M.
タイトル Antiproliferative effects of the readily extractable fractions prepared from various citrus juices on several cancer cell lines.
ジャーナル J Agric Food Chem
Abstract To eliminate the masking effect by flavonoid glycosides, which comprise approximately 70% of conventionally prepared sample, the readily extractable fraction from Citrus juice, which was prepared by adsorbing on HP-20 resin and eluting with ethanol and acetone from the resin, was subjected to antiproliferative tests against several cancer cell lines. Screening of 34 Citrus juices indicated that King (Citrus nobilis) strongly inhibited proliferation of all cancer cell lines examined. Sweet lime and Kabuchi inhibited three of the four cancer cell lines. In contrast, these samples were substantially less cytotoxic toward normal human cell lines.
巻・号 47(7)
ページ 2509-12
公開日 1999-7-1
DOI 10.1021/jf9812228
PII jf9812228
PMID 10552518
MeSH Antineoplastic Agents, Phytogenic / isolation & purification Antineoplastic Agents, Phytogenic / pharmacology* Beverages / analysis* Cell Division / drug effects* Citrus / chemistry* Citrus / classification Humans Species Specificity Tumor Cells, Cultured
IF 4.192
引用数 26
WOS 分野 AGRICULTURE, MULTIDISCIPLINARY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY
リソース情報
ヒト・動物細胞 TGBC11TKB(RCB1148) A549(RCB0098) B16 melanoma 4A5(RCB0557) CCRF-HSB-2(RCB0016)