RRC ID 40072
著者 Eguchi H, Toibana T, Hotta F, Miyamoto T, Mitamura Y, Yaguchi T.
タイトル Severe fungal sclerokeratitis caused by Metarhizium anisopliae: a case report and literature review.
ジャーナル Mycoses
Abstract To date, there has been only one published report on the infectious sclerokeratitis caused by Metarhizium anisopliae, which is an entomopathogenic fungus. Regarding corneal infection, three reports have been published to date. Although the prognoses of the corneal infections are favourable, prognosis when scleral infection is involved is very poor. A 76-year-old patient presented with foreign body sensation in the left eye. Microscopic examination with Fungi Flora Y staining of the corneal scraping revealed fungal infection. The conjunctiva was melted by the infection over a wide area. Although intensive medications were administered, an emergency surgery was necessary because scleral thinning, corneal perforation and lens prolapse occurred. The fungal isolate was identified as M. anisopliae by sequencing the internal transcribed spacer region. Herein, we report the second known case worldwide of M. anisopliae sclerokeratitis, and we review the literature related to the ocular infections.
巻・号 58(2)
ページ 88-92
公開日 2015-2-1
DOI 10.1111/myc.12279
PMID 25590990
MeSH Aged Antifungal Agents / pharmacology Antifungal Agents / therapeutic use Corneal Perforation / etiology Diagnostic Errors Echinocandins / pharmacology Eye Infections, Fungal / microbiology* Eye Infections, Fungal / therapy Humans Japan Keratitis / microbiology* Keratitis / therapy Lipopeptides / pharmacology Male Metarhizium / drug effects Metarhizium / isolation & purification* Metarhizium / ultrastructure Micafungin Scleritis / microbiology* Scleritis / therapy
IF 3.575
引用数 14
WOS 分野 DERMATOLOGY MYCOLOGY
リソース情報
病原微生物 IFM 61840