Reference - Detail
| RRC ID | 40999 |
|---|---|
| Author | Ishii T, Nonaka K, Sugawara A, Iwatsuki M, Masuma R, Hirose T, Sunazuka T, Ōmura S, Shiomi K. |
| Title | Cinatrins D and E, and virgaricin B, three novel compounds produced by a fungus, Virgaria boninensis FKI-4958. |
| Journal | J Antibiot (Tokyo) |
| Abstract |
Two new hydroxycitric acid lactone derivatives named cinatrins D (1) and E (2), and a new γ-lactam, virgaricin B (3), along with a known similar compound, virgaricin (4), were isolated from a fermentation broth of the fungus Virgaria boninensis FKI-4958. The absolute stereo structures of the new compounds were established by a combination of spectroscopic methods and chemical modifications. All three newly discovered compounds possessed weak antibacterial activity. |
| Volume | 68(10) |
| Pages | 633-7 |
| Published | 2015-10-1 |
| DOI | 10.1038/ja.2015.45 |
| PII | ja201545 |
| PMID | 25899122 |
| MeSH | Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification Anti-Bacterial Agents / pharmacology* Ascomycota / chemistry* Bacteria / drug effects Citrates / chemistry Citrates / isolation & purification Citrates / pharmacology* Fermentation Lactams / chemistry Lactams / isolation & purification Lactams / pharmacology* Lactones / chemistry Lactones / isolation & purification Lactones / pharmacology* Microbial Sensitivity Tests Molecular Conformation Soil Microbiology |
| IF | 2.668 |
| Times Cited | 6 |
| WOS Category | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY IMMUNOLOGY |
| Resource | |
| General Microbes | JCM 18623 JCM 18624 |