論文 - 詳細
| RRC ID | 41499 |
|---|---|
| 著者 | Wang LQ, Min BS, Li Y, Nakamura N, Qin GW, Li CJ, Hattori M. |
| タイトル | Annonaceous acetogenins from the leaves of Annona montana. |
| ジャーナル | Bioorg Med Chem |
| Abstract |
A novel Annonaceous acetogenin, montanacin F, with a new type of terminal lactone unit, was isolated from the leaves of Annona montana. Its structure was determined on the basis of spectral evidences and chemical methods, and a possible biosynthetic pathway was discussed. In addition, the cytotoxicity of montanacin F was evaluated in vitro against Lewis lung carcinoma (LLC) tumor cell lines. Furthermore, the previously isolated cytotoxic acetogenin annonacin against LLC was examined for in vivo antitumor activity with LLC tumor cells. |
| 巻・号 | 10(3) |
| ページ | 561-5 |
| 公開日 | 2002-3-1 |
| DOI | 10.1016/s0968-0896(01)00303-0 |
| PII | S0968089601003030 |
| PMID | 11814843 |
| MeSH | Animals Annonaceae / chemistry* Antineoplastic Agents / chemistry* Antineoplastic Agents / isolation & purification Antineoplastic Agents / pharmacology Carcinoma, Lewis Lung / drug therapy Female Furans / chemistry* Furans / isolation & purification Furans / pharmacology Injections, Intraperitoneal Lactones / chemistry* Lactones / isolation & purification Lactones / pharmacology Mice Plant Leaves / chemistry Tumor Cells, Cultured / transplantation |
| IF | 3.073 |
| 引用数 | 21 |
| WOS 分野 | CHEMISTRY, ORGANIC CHEMISTRY, MEDICINAL BIOCHEMISTRY & MOLECULAR BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 各媒体での言及数の合計 | 0 |
| リソース情報 | |
| ヒト・動物細胞 | LLC(RCB0558) |