論文 - 詳細
| RRC ID | 41949 |
|---|---|
| 著者 | Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M, Nozawa Y. |
| タイトル | Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. |
| ジャーナル | J Nat Prod |
| Abstract |
We examined the effects of six xanthones from the pericarps of mangosteen, Garcinia mangostana, on the cell growth inhibition of human leukemia cell line HL60. All xanthones displayed growth inhibitory effects. Among them, alpha-mangostin showed complete inhibition at 10 microM through the induction of apoptosis. |
| 巻・号 | 66(8) |
| ページ | 1124-7 |
| 公開日 | 2003-8-1 |
| DOI | 10.1021/np020546u |
| PMID | 12932141 |
| MeSH | Apoptosis / drug effects* Blotting, Western Garcinia / chemistry* HL-60 Cells / drug effects Humans Indonesia Inhibitory Concentration 50 Leukemia Molecular Structure Plants, Medicinal / chemistry* Stereoisomerism Tumor Cells, Cultured / drug effects Xanthones / chemistry Xanthones / isolation & purification* Xanthones / pharmacology |
| IF | 3.782 |
| 引用数 | 144 |
| WOS 分野 | CHEMISTRY, MEDICINAL PHARMACOLOGY & PHARMACY PLANT SCIENCES |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 8 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | K562(RCB0027) HL60(RCB0041) U-937 DE-4(RCB0435) |