論文 - 詳細
| RRC ID | 42111 |
|---|---|
| 著者 | Tsukushi Y, Kido N, Saeki K, Sugiyama T, Koide N, Mori I, Yoshida T, Yokochi T. |
| タイトル | Characteristic biological activities of lipopolysaccharides from Sinorhizobium and Mesorhizobium. |
| ジャーナル | J Endotoxin Res |
| Abstract |
The biological actions of lipopolysaccharides (LPSs) from Sinorhizobium meliloti, Mesorhizobium loti and Escherichia coli were compared. In biological activities including lethality, production of tumor necrosis factor (TNF)-alpha and nitric oxide (NO), adjuvant action and Limulus activity, LPS from S. meliloti exhibited stronger actions than LPS from M. loti, but had a weaker action than LPS from E. coli. On the other hand, M. loti LPS showed a higher activity to activate human complement than S. meliloti LPS. Further, there was a significant difference in polymyxin B binding between S. meliloti LPS and M. loti LPS, suggesting a difference in the lipid A structure. LPSs from S. meliloti and M. loti seem to exhibit characteristic biological actions that may be dependent on the difference in the lipid A structure. |
| 巻・号 | 10(1) |
| ページ | 25-31 |
| 公開日 | 2004-1-1 |
| DOI | 10.1179/096805104225003799 |
| PMID | 15025821 |
| MeSH | Animals Biological Assay Escherichia coli / pathogenicity Horseshoe Crabs Lipopolysaccharides / isolation & purification* Lipopolysaccharides / pharmacology* Nitric Oxide / analysis Proteobacteria / pathogenicity* Sinorhizobium / pathogenicity* Structure-Activity Relationship Tumor Necrosis Factor-alpha / biosynthesis |
| 引用数 | 8 |
| WOS 分野 | MEDICINE, RESEARCH & EXPERIMENTAL IMMUNOLOGY MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | RAW 264(RCB0535) |