論文 - 詳細
| RRC ID | 43130 |
|---|---|
| 著者 | Ishii T, Wada A, Tsuzuki S, Casolaro M, Ito Y. |
| タイトル | Copolymers including L-histidine and hydrophobic moiety for preparation of nonbiofouling surface. |
| ジャーナル | Biomacromolecules |
| Abstract |
A new type of copolymer composed of l-histidine (ampholyte) and n-butyl methacrylate (hydrophobic moiety) was developed for the preparation of nonbiofouling surfaces. The copolymer adsorbed onto resin surfaces and made the surface very hydrophilic. The hydrophilization effect was higher than that of bovine serum albumin (BSA). When polystyrene surfaces were coated with the copolymer, both the nonspecific adsorption of protein and the adhesion of cells were significantly reduced in comparison with BSA coating. The newly synthesized polymer is a new and useful candidate for the preparation of nonbiofouling surfaces. |
| 巻・号 | 8(11) |
| ページ | 3340-4 |
| 公開日 | 2007-11-1 |
| DOI | 10.1021/bm070420h |
| PMID | 17915936 |
| MeSH | Animals Cattle Cell Adhesion Cell Line Cell Survival Histidine / chemistry* Horseradish Peroxidase / chemistry Horseradish Peroxidase / metabolism Hydrophobic and Hydrophilic Interactions* Mice Molecular Weight Polymers / chemistry* Serum Albumin, Bovine / chemistry Serum Albumin, Bovine / metabolism Surface Properties |
| IF | 6.092 |
| 引用数 | 13 |
| WOS 分野 | POLYMER SCIENCE CHEMISTRY, ORGANIC BIOCHEMISTRY & MOLECULAR BIOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | MC3T3-E1(RCB1126) |