論文 - 詳細
| RRC ID | 44192 |
|---|---|
| 著者 | Takahashi M, Asikin Y, Takara K, Wada K. |
| タイトル | Screening of medicinal and edible plants in Okinawa, Japan, for enhanced proliferative and collagen synthesis activities in NB1RGB human skin fibroblast cells. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
To identify plants with bioactive potential for skin care, methanol extracts of 56 plant parts from 47 medical and edible plants cultivated in Okinawa were tested for their proliferative effects on NB1RGB skin fibroblast cells. Extracts from six plants, Bischofia javanica, Colocasia esculenta, Melaleuca alternifolia, Piper angustifolia, Jasminum sambac, and Curcuma longa, showed higher NB1RGB cell proliferation activity (>10%) than the control, at various concentrations. Among the six extracts, only the C. longa extract caused an increase in collagen synthesis in NB1RGB cells, as compared to treatment with the positive control, ascorbic acid (AsA). Expression of the collagen synthesis marker, transforming growth factor-β1, was higher after treatment with the C. longa extract than with AsA. |
| 巻・号 | 76(12) |
| ページ | 2317-20 |
| 公開日 | 2012-1-1 |
| DOI | 10.1271/bbb.120478 |
| PII | DN/JST.JSTAGE/bbb/120478 |
| PMID | 23221723 |
| MeSH | Cell Line Cell Proliferation / drug effects Collagen Type I / biosynthesis* Drug Evaluation, Preclinical Fibroblasts / cytology* Humans Japan Plant Extracts / pharmacology* Plants, Edible / chemistry* Plants, Medicinal / chemistry* Skin / cytology* |
| IF | 1.516 |
| 引用数 | 2 |
| WOS 分野 | BIOCHEMISTRY & MOLECULAR BIOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | NB1RGB(RCB0222) |