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  • Search Condition : Filter (MeSH = Drug Evaluation, Preclinical)
Species Resource
Pathogenic microorganisms IFM 40005 , IFM 40006 , IFM 40007 , IFM 40009 Studies on peptide antibiotics, leucinostatins. I. Separation, physico-chemical properties and biological activities of leucinostatins A and B.
Mice C57BL-p53+/-(RBRC01361) Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts.
DNA material Genome Network human cDNA clone IRAL015K15 (HGY086255) , IRAL037F09 (HGY094929) , IRAK022O02 (HGX009138) , IRAL007N16 (HGY083128) , IRAL016K22 (HGY086662) , IRAL005A23 (HGY082023) , IRAK004O20 (HGX001956) , IRAL006E09 (HGY082505) , IRAL004F23 (HGY081743) A practical fluorogenic substrate for high-throughput screening of glutathione S-transferase inhibitors.
Human and Animal Cells Fucoidan enhances intestinal barrier function by upregulating the expression of claudin-1.
Human and Animal Cells Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss.
Human and Animal Cells Evaluation of three-dimensional cultured HepG2 cells in a nano culture plate system: an in vitro human model of acetaminophen hepatotoxicity.
Human and Animal Cells Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells.
Human and Animal Cells Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter niemann-pick c1-like 1 in caco-2 cells and rats.
Human and Animal Cells Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity.
Human and Animal Cells Preclinical testing of virotherapeutics for primary and secondary tumors of the liver.
Human and Animal Cells Bimodal effect of retinoic acid on melanocyte differentiation identified by time-dependent analysis.
Human and Animal Cells In vitro and in vivo evaluation of a preservative-free cationic emulsion of latanoprost in corneal wound healing models.
Human and Animal Cells Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Human and Animal Cells Screening of medicinal and edible plants in Okinawa, Japan, for enhanced proliferative and collagen synthesis activities in NB1RGB human skin fibroblast cells.
Human and Animal Cells Evaluation of anti-inflammatory drug-conjugated silicon quantum dots: their cytotoxicity and biological effect.
Prokaryotes E. coli NA Endogenous ethanol affects biopolyester molecular weight in recombinant Escherichia coli.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
C.elegans tm3223 Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.
Silkworms [Drug discovery for treatment against diabetes by using hyperglycemic silkworms].
Silkworms [Silkworm as a model animal for drug development].