| RRC ID |
44352
|
| Author |
Ijiri D, Higuchi A, Saegusa A, Miura M, Matsubara T, Kanai Y, Ohtsuka A, Hirabayashi M.
|
| Title |
Role of prolactin-like protein (PRL-L) in cold-induced increase of muscle mass in chicks.
|
| Journal |
Gen Comp Endocrinol
|
| Abstract |
This study examined the hypothesis that a novel prolactin-like protein gene (PRL-L) is involved in cold-induced growth of skeletal muscle in chicks. Six-day-old chicks (Gallus gallus domesticus) were exposed to cold at 4°C or kept warm at 30°C for 24h. Cold exposure induced significant increases in PRL-L expression that coincided with increases in the weight of the sartorius muscle, which comprises both fast- and slow-twitch fibers. Meanwhile, no induction of PRL-L mRNA was observed in the heart, liver, kidney, brain, or fat. Myoblast cells that expressed PRL-L mRNA grew faster than untransduced cells in media containing 2% serum. These results suggested that PRL-L might be involved in in controlling cold-induced muscle growth of chicks.
|
| Volume |
186
|
| Pages |
94-100
|
| Published |
2013-6-1
|
| DOI |
10.1016/j.ygcen.2013.03.007
|
| PII |
S0016-6480(13)00127-5
|
| PMID |
23523997
|
| MeSH |
Animals
Chickens
Cold Temperature
Muscle, Skeletal / metabolism*
Pregnancy Proteins / metabolism*
|
| IF |
2.428
|
| Times Cited |
5
|
|
WOS Category
|
ENDOCRINOLOGY & METABOLISM
|
| Resource |
| Human and Animal Cells |
C2C12(RCB0987) |
