RRC ID 45264
Author Shimada M, Ozawa M, Iwamoto K, Fukuyama Y, Kishida A, Ohsaki A.
Title A lanostane triterpenoid and three cholestane sterols from Tilia kiusiana.
Journal Chem Pharm Bull (Tokyo)
Abstract Kiusianins A-D (1-4) were isolated from the leaves of a Japanese endemic plant, Tilia kiusiana, together with 14 known compounds. The structures of a new lanostane-type triterpenoid 1 and three new cholestane-type sterols 2-4 were elucidated by spectroscopic methods, including two dimensional (2D) NMR. All the compounds isolated were evaluated for their cytotoxicity against two human cancer cell lines, HeLa and HL-60.
Volume 62(9)
Pages 937-41
Published 2014-1-1
DOI 10.1248/cpb.c14-00200
PII DN/JST.JSTAGE/cpb/c14-00200
PMID 25177022
MeSH Cell Line, Tumor Cholestanes / isolation & purification* Humans Magnetic Resonance Spectroscopy Sterols / isolation & purification* Tilia / chemistry* Triterpenes / isolation & purification*
IF 1.416
Times Cited 9
WOS Category PHARMACOLOGY & PHARMACY CHEMISTRY, MULTIDISCIPLINARY CHEMISTRY, MEDICINAL
Resource
Human and Animal Cells