RRC ID 46734
Author Martin R, Entchev EV, Kurzchalia TV, Knölker HJ.
Title Steroid hormones controlling the life cycle of the nematode Caenorhabditis elegans: stereoselective synthesis and biology.
Journal Org Biomol Chem
Abstract Cholesterol-derived hormones, the dafachronic acids, play a major role in controlling the life cycle and initiating dauer larva formation of the nematode Caenorhabditis elegans. This Perspective describes recent progress in the synthesis of these steroid hormones and their biological function.
Volume 8(4)
Pages 739-50
Published 2010-2-21
DOI 10.1039/b918488k
PMID 20135027
MeSH Animals Caenorhabditis elegans / physiology* Caenorhabditis elegans Proteins / biosynthesis Caenorhabditis elegans Proteins / physiology* Cholesterol / pharmacology Gene Expression Regulation, Developmental / drug effects Gene Expression Regulation, Developmental / physiology Genes, Helminth Hormones / pharmacology* Larva / drug effects Larva / physiology Life Cycle Stages / drug effects* Life Cycle Stages / physiology Longevity / drug effects Signal Transduction / physiology Stereoisomerism Steroids / pharmacology*
IF 3.412
Times Cited 18
C.elegans tm1781