Reference - Detail
| RRC ID | 46769 |
|---|---|
| Author | Hagiwara D, Takahashi H, Fujimoto M, Sugahara M, Misawa Y, Gonoi T, Itoyama S, Watanabe A, Kamei K. |
| Title | Multi-azole resistant Aspergillus fumigatus harboring Cyp51A TR46/Y121F/T289A isolated in Japan. |
| Journal | J Infect Chemother |
| Abstract |
Multi-azole resistant Aspergillus fumigatus carrying TR46/Y121F/T289A was isolated from a patient in Japan in Dec 2013. This strain grouped into the same clade of the ones which were clinically isolated in France and Germany. A. fumigatus harboring this mutation could be rapidly diffused outside the Eurasian continent. |
| Volume | 22(8) |
| Pages | 577-9 |
| Published | 2016-8-1 |
| DOI | 10.1016/j.jiac.2016.01.015 |
| PII | S1341-321X(16)00036-2 |
| PMID | 26898666 |
| MeSH | Aged Antifungal Agents / therapeutic use* Aspergillosis / drug therapy* Aspergillosis / microbiology Aspergillus fumigatus / drug effects* Aspergillus fumigatus / genetics Aspergillus fumigatus / isolation & purification* Azoles / therapeutic use* Drug Resistance, Fungal / drug effects Drug Resistance, Fungal / genetics* Female France Fungal Proteins / genetics* Germany Humans Japan Microbial Sensitivity Tests / methods Mutation / genetics Voriconazole / therapeutic use |
| IF | 1.722 |
| Times Cited | 23 |
| WOS Category | PHARMACOLOGY & PHARMACY INFECTIOUS DISEASES |
| Resource | |
| Pathogenic microorganisms | NA |