RRC ID 46856
著者 Kubota T, Kamijyo Y, Takahashi-Nakaguchi A, Fromont J, Gonoi T, Kobayashi J.
タイトル Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge Amphimedon sp.
ジャーナル Org Lett
Abstract A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).
巻・号 15(3)
ページ 610-2
公開日 2013-2-1
DOI 10.1021/ol3034274
PMID 23343122
MeSH Alkaloids / chemistry Alkaloids / isolation & purification* Alkaloids / pharmacology Animals Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification* Anti-Bacterial Agents / pharmacology Carbazoles Drug Screening Assays, Antitumor Humans Japan Microbial Sensitivity Tests Porifera / chemistry* Staphylococcus aureus / drug effects
IF 6.091
引用数 18
WOS 分野 CHEMISTRY, ORGANIC
リソース情報
病原微生物 NA