RRC ID 47024
著者 Xi L, Sun J, Lu C, Liu H, Xie Z, Fukushima K, Takizawa K, Najafzadeh MJ, De Hoog GS.
タイトル Molecular diversity of Fonsecaea (Chaetothyriales) causing chromoblastomycosis in southern China.
ジャーナル Med Mycol
Abstract Chromoblastomycosis is a chronic, cutaneous and subcutaneous infection caused by members of the order Chaetothyriales and commonly found in China. Among the etiologic agents, members of the genus Cladophialophora are predominant in northern China. Alternatively, Fonsecaea spp. are particularly common in southern China. However, the identification of Fonsecaea isolates recovered in China is difficult due to the fact that different species lack distinctive morphological characters. Therefore, the identification of 24 Fonsecaea isolates from symptomatic patients were re-evaluated by using morphology, ITS rDNA sequence diversity and partly through the use of randomly amplified polymorphic DNA (RAPD) typing. Twenty strains, including a morphological mutant were found to be Fonsecaea monophora, while four strains corresponded to F. pedrosoi. We have demonstrated that Fonsecaea monophora is the predominant etiologic agent of chromoblastomycosis in southern China and populations showed marked geographic structuring.
巻・号 47(1)
ページ 27-33
公開日 2009-2-1
DOI 10.1080/13693780802468209
PII 904846923
PMID 18951291
MeSH Ascomycota / classification* Ascomycota / genetics Ascomycota / physiology Ascomycota / ultrastructure China / epidemiology Chromoblastomycosis / epidemiology* Chromoblastomycosis / microbiology Chromoblastomycosis / pathology DNA, Fungal / analysis DNA, Ribosomal DNA, Ribosomal Spacer / analysis Genetic Variation* Humans Mycological Typing Techniques Phylogeny Random Amplified Polymorphic DNA Technique Sequence Analysis, DNA Species Specificity
IF 2.822
引用数 53
WOS 分野 VETERINARY SCIENCES MYCOLOGY INFECTIOUS DISEASES
リソース情報
病原微生物 IFM 4886 IFM 41704 IFM 41705 IFM 41931 IFM 46410