RRC ID 47658
著者 Oonuma K, Tanaka M, Nishitsuji K, Kato Y, Shimai K, Kusakabe TG.
タイトル Revised lineage of larval photoreceptor cells in Ciona reveals archetypal collaboration between neural tube and neural crest in sensory organ formation.
ジャーナル Dev. Biol.
Abstract The Ciona intestinalis larva has two distinct photoreceptor organs, a conventional pigmented ocellus and a nonpigmented ocellus, that are asymmetrically situated in the brain. The ciliary photoreceptor cells of these ocelli resemble visual cells of the vertebrate retina. Precise elucidation of the lineage of the photoreceptor cells will be key to understanding the developmental mechanisms of these cells as well as the evolutionary relationships between the photoreceptor organs of ascidians and vertebrates. Photoreceptor cells of the pigmented ocellus have been thought to develop from anterior animal (a-lineage) blastomeres, whereas the developmental origin of the nonpigmented ocellus has not been determined. Here, we show that the photoreceptor cells of both ocelli develop from the right anterior vegetal hemisphere: those of the pigmented ocellus from the right A9.14 cell and those of the nonpigmented ocellus from the right A9.16 cell. The pigmented ocellus is formed by a combination of two lineages of cells with distinct embryonic origins: the photoreceptor cells originate from a medial portion of the A-lineage neural plate, while the pigment cell originates from the lateral edge of the a-lineage neural plate. In light of the recently proposed close evolutionary relationship between the ocellus pigment cell of ascidians and the cephalic neural crest of vertebrates, the ascidian ocellus may represent a prototypic contribution of the neural crest to a cranial sensory organ.
巻・号 420(1)
ページ 178-185
公開日 2016-12-1
DOI 10.1016/j.ydbio.2016.10.014
PII S0012-1606(16)30612-1
PMID 27789227
MeSH Animals Cell Count Cell Lineage* Ciona intestinalis / cytology* Ciona intestinalis / metabolism Larva / cytology Neural Crest / cytology* Neural Tube / cytology* Optical Imaging Photoreceptor Cells, Invertebrate / cytology* Photoreceptor Cells, Invertebrate / metabolism Pigmentation Retinal Pigment Epithelium / cytology Sense Organs / cytology*
IF 2.944
引用数 0
カタユウレイボヤ・(ニッポンウミシダ) Wild C. int