RRC ID 48018
著者 Wang Q, Tanigawa H, Fujita I.
タイトル Postnatal Development of Intrinsic Horizontal Axons in Macaque Inferior Temporal and Primary Visual Cortices.
ジャーナル Cereb Cortex
Abstract Two distinct areas along the ventral visual stream of monkeys, the primary visual (V1) and inferior temporal (TE) cortices, exhibit different projection patterns of intrinsic horizontal axons with patchy terminal fields in adult animals. The differences between the patches in these 2 areas may reflect differences in cortical representation and processing of visual information. We studied the postnatal development of patches by injecting an anterograde tracer into TE and V1 in monkeys of various ages. At 1 week of age, labeled patches with distribution patterns reminiscent of those in adults were already present in both areas. The labeling intensity of patches decayed exponentially with projection distance in monkeys of all ages in both areas, but this trend was far less evident in TE. The number and extent of patches gradually decreased with age in V1, but not in TE. In V1, axonal and bouton densities increased postnatally only in patches with short projection distances, whereas in TE this density change occurred in patches with various projection distances. Thus, patches with area-specific distribution patterns are formed early in life, and area-specific postnatal developmental processes shape the connectivity of patches into adulthood.
巻・号 27(4)
ページ 2708-2726
公開日 2017-4-1
DOI 10.1093/cercor/bhw105
PII bhw105
PMID 27114175
MeSH Animals Axons* Macaca Neural Pathways / growth & development* Neurogenesis* Temporal Lobe / growth & development* Visual Cortex / growth & development*
IF 5.043
引用数 3
WOS 分野 NEUROSCIENCES
リソース情報
ニホンザル