Reference - Detail
|Author||Takumi T, Ohkubo H, Nakanishi S.|
|Title||Cloning of a membrane protein that induces a slow voltage-gated potassium current.|
A rat kidney messenger RNA that induces a slowly activating, voltage-dependent potassium current on its expression in Xenopus oocytes was identified by combining molecular cloning with an electrophysiological assay. The cloned complementary DNA encodes a novel membrane protein that consists of 130 amino acids with a single putative transmembrane domain. This protein differs from the known ion channel proteins but is involved in the induction of selective permeation of potassium ions by membrane depolarization.
|MeSH||Amino Acid Sequence Animals Base Sequence Blotting, Northern Cloning, Molecular DNA / genetics Electric Conductivity Membrane Potentials Membrane Proteins / genetics* Molecular Sequence Data Molecular Weight Potassium Channels / physiology* Rats Xenopus laevis|
|WOS Category||BIOCHEMISTRY & MOLECULAR BIOLOGY|
|DNA material||pKI 27 (RDB13187)|