論文 - 詳細
| RRC ID | 50565 |
|---|---|
| 著者 | Nishimura T, Yamada K, Fujimori C, Kikuchi M, Kawasaki T, Siegfried KR, Sakai N, Tanaka M. |
| タイトル | Germ cells in the teleost fish medaka have an inherent feminizing effect. |
| ジャーナル | PLoS Genet |
| Abstract |
AUTHOR SUMMARY:Germ cells are the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in teleosts revealed another essential role of germ cells: feminizing the gonads. In our study, medaka mutants in which gametogenesis was blocked at specific stages provides the novel view that the feminizing effect of germ cells occurs in parallel with other reproductive elements, such as meiosis, the sexual fate decision of germ cells, and gametogenesis. Germ cells in medaka may have a potential to feminize gonads at the moment they have developed. |
| 巻・号 | 14(3) |
| ページ | e1007259 |
| 公開日 | 2018-3-1 |
| DOI | 10.1371/journal.pgen.1007259 |
| PII | PGENETICS-D-17-01674 |
| PMID | 29596424 |
| PMC | PMC5875746 |
| MeSH | Animals Cell Lineage Female Feminization* Gametogenesis Germ Cells / cytology* Male Meiosis Oryzias / genetics* Sex Differentiation |
| IF | 5.175 |
| 引用数 | 8 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 1480 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| メダカ | fosmid clone (GOLWFno462_j06) OK-Cab (MT830) |