論文 - 詳細
| RRC ID | 50671 |
|---|---|
| 著者 | Sato T, Kusuhara S, Yokoi W, Ito M, Miyazaki K. |
| タイトル | Prebiotic potential of L-sorbose and xylitol in promoting the growth and metabolic activity of specific butyrate-producing bacteria in human fecal culture. |
| ジャーナル | FEMS Microbiol Ecol |
| Abstract |
Dietary low-digestible carbohydrates (LDCs) affect gut microbial metabolism, including the production of short-chain fatty acids. The ability of various LDCs to promote butyrate production was evaluated in in vitro human fecal cultures. Fecal suspensions from five healthy males were anaerobically incubated with various LDCs. L-Sorbose and xylitol markedly promoted butyrate formation in cultures. Bacterial 16S rRNA gene-based denaturing gradient gel electrophoresis analyses of these fecal cultures revealed a marked increase in the abundance of bacteria closely related to the species Anaerostipes hadrus or A. caccae or both, during enhanced butyrate formation from L-sorbose or xylitol. By using an agar plate culture, two strains of A. hadrus that produced butyrate from each substrate were isolated from the feces of two donors. Furthermore, of 12 species of representative colonic butyrate producers, only A. hadrus and A. caccae demonstrated augmented butyrate production from L-sorbose or xylitol. These findings suggest that L-sorbose and xylitol cause prebiotic stimulation of the growth and metabolic activity of Anaerostipes spp. in the human colon. |
| 巻・号 | 93(1) |
| 公開日 | 2017-1-1 |
| DOI | 10.1093/femsec/fiw227 |
| PII | fiw227 |
| PMID | 27810878 |
| MeSH | Bacteria / classification Bacteria / growth & development* Bacteria / isolation & purification Bacteria / metabolism* Butyrates / metabolism* Colon / microbiology Feces / microbiology* Fermentation Gastrointestinal Microbiome Humans Male Prebiotics / analysis* Sorbose / metabolism* Xylitol / metabolism* |
| IF | 3.675 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 8 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM 1772 |