論文 - 詳細
RRC ID | 51580 |
---|---|
著者 | Ribeiro C, Correia V, Martins P, Gama FM, Lanceros-Mendez S. |
タイトル | Proving the suitability of magnetoelectric stimuli for tissue engineering applications. |
ジャーナル | Colloids Surf B Biointerfaces |
Abstract |
A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to ≈ 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli. |
巻・号 | 140 |
ページ | 430-436 |
公開日 | 2016-4-1 |
DOI | 10.1016/j.colsurfb.2015.12.055 |
PII | S0927-7765(15)30403-3 |
PMID | 26797659 |
MeSH | Alloys / chemistry Animals Cell Line Cell Proliferation* Dysprosium / chemistry Electric Stimulation Hydrocarbons, Fluorinated / chemistry Iron / chemistry Magnetic Fields* Membranes, Artificial Mice Microscopy, Fluorescence Osteoblasts / cytology* Reproducibility of Results Terbium / chemistry Tissue Engineering / instrumentation Tissue Engineering / methods* Tissue Scaffolds / chemistry Vinyl Compounds / chemistry |
IF | 4.389 |
引用数 | 58 |
リソース情報 | |
ヒト・動物細胞 | MC3T3-E1(RCB1126) |