RRC ID 51580
著者 Ribeiro C, Correia V, Martins P, Gama FM, Lanceros-Mendez S.
タイトル Proving the suitability of magnetoelectric stimuli for tissue engineering applications.
ジャーナル Colloids Surf B Biointerfaces
Abstract A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to ≈ 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli.
巻・号 140
ページ 430-436
公開日 2016-4-1
DOI 10.1016/j.colsurfb.2015.12.055
PII S0927-7765(15)30403-3
PMID 26797659
MeSH Alloys / chemistry Animals Cell Line Cell Proliferation* Dysprosium / chemistry Electric Stimulation Hydrocarbons, Fluorinated / chemistry Iron / chemistry Magnetic Fields* Membranes, Artificial Mice Microscopy, Fluorescence Osteoblasts / cytology* Reproducibility of Results Terbium / chemistry Tissue Engineering / instrumentation Tissue Engineering / methods* Tissue Scaffolds / chemistry Vinyl Compounds / chemistry
IF 4.389
引用数 58
リソース情報
ヒト・動物細胞 MC3T3-E1(RCB1126)