| RRC ID |
51808
|
| 著者 |
Koyama S, Narita E, Shimizu Y, Suzuki Y, Shiina T, Taki M, Shinohara N, Miyakoshi J.
|
| タイトル |
Effects of Long-Term Exposure to 60 GHz Millimeter-Wavelength Radiation on the Genotoxicity and Heat Shock Protein (Hsp) Expression of Cells Derived from Human Eye.
|
| ジャーナル |
Int J Environ Res Public Health
|
| Abstract |
Human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cells derived from the human eye were exposed to 60 gigahertz (GHz) millimeter-wavelength radiation for 24 h. There was no statistically significant increase in the micronucleus (MN) frequency in cells exposed to 60 GHz millimeter-wavelength radiation at 1 mW/cm² compared with sham-exposed controls and incubator controls. The MN frequency of cells treated with bleomycin for 1 h provided positive controls. The comet assay, used to detect DNA strand breaks, and heat shock protein (Hsp) expression also showed no statistically significant effects of exposure. These results indicate that exposure to millimeter-wavelength radiation has no effect on genotoxicity in human eye cells.
|
| 巻・号 |
13(8)
|
| 公開日 |
2016-8-8
|
| DOI |
10.3390/ijerph13080802
|
| PII |
ijerph13080802
|
| PMID |
27509516
|
| PMC |
PMC4997488
|
| MeSH |
Bleomycin
Cell Line / radiation effects*
Comet Assay
DNA Damage / radiation effects*
Eye*
Heat-Shock Proteins / metabolism*
Humans
Lens, Crystalline
Microwaves
Radiation Exposure / adverse effects*
Radio Waves / adverse effects*
|
| IF |
2.849
|
| 引用数 |
7
|
| リソース情報 |
| ヒト・動物細胞 |
HCE-T(RCB2280) |
