RRC ID 51844
Author Teimouri A, Azadi M, Shams Ghahfarokhi Z, Razavizadeh R.
Title Preparation and characterization of novel β-chitin/nanodiopside/nanohydroxyapatite composite scaffolds for tissue engineering applications.
Journal J Biomater Sci Polym Ed
Abstract β-chitin/nanodiopside/nanohydroxyapatite (CT/nDP/nHAp) composite scaffolds were synthesized from the combination of chitin, nDP, and nHAp in different inorganic/organic weight ratios by the freeze-drying technique. The prepared nHAp, and composite scaffolds were characterized by BET, TG, FT-IR, SEM, and XRD studies. The composite scaffolds had 50-75% porosities with well-defined interconnected porous networks. Moreover, investigation of the cell attachment and viability using MTT, DMEM solution, and mouse preosteoblast cell proved the cytocompatibile nature of the composite scaffolds with improved cell adhesion. All these results mainly illustrated that this composite could be a candidate for bone tissue engineering application.
Volume 28(1)
Pages 1-14
Published 2017-1-1
DOI 10.1080/09205063.2016.1231437
PMID 27604099
MeSH Biocompatible Materials / chemistry* Biocompatible Materials / pharmacology Cell Line Chitin / chemistry* Durapatite / chemistry* Materials Testing Mechanical Phenomena Silicic Acid / chemistry* Tissue Engineering* Tissue Scaffolds / chemistry*
IF 2.69
Times Cited 10
Resource
Human and Animal Cells MC3T3-E1(RCB1126)