論文 - 詳細
| RRC ID | 51889 |
|---|---|
| 著者 | Liu W, Al-Oweini R, Meadows K, Bassil BS, Lin Z, Christian JH, Dalal NS, Bossoh AM, Mbomekallé IM, de Oliveira P, Iqbal J, Kortz U. |
| タイトル | CrIII-Substituted Heteropoly-16-Tungstates [CrIII2(B-β-XIVW8O31)2]14- (X = Si, Ge): Magnetic, Biological, and Electrochemical Studies. |
| ジャーナル | Inorg Chem |
| Abstract |
The dichromium(III)-containing heteropoly-16-tungstates [CrIII2(B-β-SiIVW8O31)2]14- (1) and [CrIII2(B-β-GeIVW8O31)2]14- (2) were prepared via a one-pot reaction of the composing elements in aqueous, basic medium. Polyanions 1 and 2 represent the first examples of CrIII-containing heteropolytungstates comprising the octatungstate unit {XW8O31} (X = Si, Ge). Magnetic studies demonstrated that, in the solid state, the two polyanions exhibit a weak antiferromagnetic interaction between the two CrIII centers with J = -3.5 ± 0.5 cm-1, with no long-range ordering down to 1.8 K. The ground-state spin of polyanions 1 and 2 was thus deduced to be 0, but the detection of a complex set of EPR signals implies that there are thermally accessible excited states containing unpaired spins resulting from the two S = 3/2 CrIII ions. A comprehensive electrochemistry study on 1 and 2 in solution was performed, and biological tests showed that both polyanions display significant antidiabetic and anticancer activities. |
| 巻・号 | 55(21) |
| ページ | 10936-10946 |
| 公開日 | 2016-11-7 |
| DOI | 10.1021/acs.inorgchem.6b01458 |
| PMID | 27768287 |
| MeSH | Animals Antineoplastic Agents / chemistry* Antineoplastic Agents / pharmacology Cell Line, Tumor Cell Survival / drug effects Chlorocebus aethiops Chromium / chemistry* Chromium / pharmacology Crystallography, X-Ray Diabetes Mellitus / drug therapy Electrochemical Techniques Electron Spin Resonance Spectroscopy Glucosidases / antagonists & inhibitors Humans Hypoglycemic Agents / chemistry* Hypoglycemic Agents / pharmacology Models, Molecular Neoplasms / drug therapy Tungsten Compounds / chemistry* Tungsten Compounds / pharmacology Vero Cells |
| IF | 4.825 |
| 引用数 | 8 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | Vero(RCB0001) |